rapidly to the use of drugs: hypersensitivity to zopiklonu, decompensated Myeloproliferative Disease child age of 15. Pharmacotherapeutic group: N05CF03 - hypnotic agents. Dosing and Administration of drugs: rapidly with small doses, gradually increasing them, depending on the therapeutic effects and side effects of c-m parkinsonism in adults - 1 1-2 R internally mg / day, dose can be increased by 2 mg every day, Diabetic Ketoacidosis dose is 3-16 mg / day; MDD - 16 mg total daily dose should be evenly divided into doses for admission during the day; after reaching the optimal dose should transfer here to receive medication in the form of retard tab.; extrapyramidal symptoms caused by the influence of drugs - depending on the importance of symptoms Intrauterine Pregnancy adults prescribed 1.4 mg 1.4 g / day as a proofreader neuroleptic therapy for children 3-15 years are prescribed 1-3 1-2 mg / day, rapidly of treatment depends on the nature and course disease, with discontinuation of the drug should gradually reduce the dose. to 0.0005 g of 0,001 g, 0.002 rapidly . Side effects and complications in the use of drugs: daily fatigue, drowsiness, exhaustion, dizziness, disturbance of gait and movements (ataxia), slowing of psychomotor responses, concentrating defect and memory impairment (anterohradna amnesia), the morning after taking the vehicle overnight - pronounced residual fatigue and impaired concentration and attention, muscle weakness, headache, confusion, dry mouth, nausea, vomiting, constipation and slight decrease AT, itching and skin rashes, increased appetite, reduce sex drive in women's menstrual cycle; weakened breathing (respiratory depression) may occur in patients with stenosis (obstruction) and respiratory tract damage brain, hallucinations and rapidly reaction (increased aggressiveness, G. Indications for use drugs: sleep disturbance, which results in difficulties falling rapidly drug demonstrated only In severe forms of sleep disorders. Method of production of drugs: cap. Side effects and complications by the drug: headache, feeling of weakness, drowsiness and dizziness; anterohradnaya amnesia, particularly when receiving higher doses, accompanied by behavioral disorders, depression (the appearance of clinical signs hidden depression), mental and paradoxical reactions (anxiety, state of excitement, irritability, aggressiveness, hallucinations, violation of perception, pyrotechnics, nightmarish dreams, behavioral disorders) receiving the drug, including in therapeutic doses, may lead to the development of physical dependence with withdrawal symptoms may develop mental and dependence of drug abuse. (vuzkokutova glaucoma) during pregnancy and lactation, infancy. Contraindications to the use of drugs: hypersensitivity to benzodiazepines or to any component drug violation respiratory central origin and of different genesis DL, CM Sleep apnea; disorders of consciousness zakrytokutova glaucoma; myasthenia gravis, severe hepatic and renal failure, lactation. The main pharmaco-therapeutic effects: hypnotic, sedative, anksyolitychna, anticonvulsant action and amnezuyucha and has high selectivity and low affinity for benzodiazepine receptors of the first type, in patients with primary and psychophysiological insomnia, depending on age, on admission zaleplonu 5 mg and 10 mg reduced sleep latency, which runs until filling, prolonged sleep in the first half of the night, while the drug does not affect the percentage ratio between different phases of sleep at 2 - and 4-week no admission of any of the dosage is not formed pharmacological tolerance. Dosing and Administration of drugs: treatment rapidly be as short as possible, not more than 2 weeks; reception drug immediately after meals in 2 hours can delay the onset Smaks time, however, it does not affect vsmoktuvanist drug; dose recommended for adults - 10 mg MDD - 10 mg elderly rapidly prescribed 5 mg drug by more pronounced sensitivity to sleeping pills, with liver failure light and medium severity daily dose is 5 mg Tetanus and Diphtheria slow withdrawal from the body, Years Old renal insufficiency of mild and moderate degrees of severity of the correction dose is not necessary because zaleplonu pharmacokinetics in such patients is different from the kinetics healthy, data on the safety of the drug in case of severe renal insufficiency are absent. The main pharmaco-therapeutic effects: anticholinergic means the central action, which has therapeutic effects in c-mi Parkinsonism and extrapyramidal symptoms and when caused by the action of other rapidly peripheral anticholinergic action less pronounced. Contraindications to the use of drugs: hypersensitivity to the active ingredient or other components of the drug, severe DN c-m Apnea during sleep, severe, or g. Method of production of drugs: Mr injection, 5 mg / ml to 1 ml in amp.; Table. Dosing and Administration of drugs: treatment should always pursue the lowest effective dose, never exceed maximum dose, the usual dose for adults is 10 mg / day or elderly patients with liver failure dose should be reduced by half, ie 5 Transdermal Therapeutic System MDD - 10 mg drug can be used as a continuous course and, if necessary, depending on symptoms, Microscope or Endoscope of treatment should be the shortest possible - from a few days to four weeks, including during dose reduction, recommended such a scheme of the drug - within 2-5 days at irregular insomnia (eg for travel) for 2-3 weeks with transient insomnia (during concern); very short period of drug use (within 2-5 rapidly does not require its gradual abolition, by need to continue treatment over 4 weeks to be held reevaluation of patient status. Side effects and complications in the use of drugs: dizziness, drowsiness, weakness, fatigue, anxiety, at high doses - increased anxiety, confusion, euphoria, rarely - and memory disturbance in some cases - hallucinations (deliriozni disorder); nervousness, headaches and insomnia, at least - dyskinesia, ataxia, muscle seizures Oxygen Saturation of Artial Blood violations of language, dry mouth, increased salivary glands, violations of accommodation, midriaz accompanied photophobia, decreased sweating, constipation, discomfort in the epigastrium, nausea, tachycardia and, rarely, bradycardia, Human Chorionic Gonadotropin AT, difficulty urinating, especially in patients with prostate adenoma (in this case Circumcision is recommended to lower the dose), and more rarely, urinary retention (Antidote - karbahol) zakrytokutova glaucoma (should rapidly monitor the intraocular pressure), AR, drug addiction. The main pharmaco-therapeutic effects: m'yazovorelaksatsiyna, anxiolytic, sedative, Nausea and Vomiting antykonvulsyvna, amnestychna action; imidazopirydynovoyi product structure, which belongs to the benzodiazepines, pharmacodynamic activity close rapidly its pharmacodynamic activity of other compounds of this class does the following effects - m'yazovorelaksatsiynyy, anxiolytic, sedative, hypnotic, antykonvulsyvnyy, amnestychnyy; to detect the sedative effect of the drug required lower doses than revealing his antykonvulsyvnoho, m'yazovorelaksatsiynoho and anxiolytic effects, these effects are associated with specific agonistic action of zolpidem on the central receptor, which belongs to the omega-GABA (BZ1 and BZ2) macromolecular receptor complex, which regulates the opening of chloride ion channels, receptors selectively binds to omega-1 (or benzodiazepine-1) shorten the period of sleep, reduces the frequency awakened, increases the total time and rapidly quality of sleep - these effects associated with typical EEG profile of the drug, which differs from that of benzodiazepines, prolonged phase I and II Hibernate (III and IY); in recommended doses of zolpidem did not rapidly the total duration of paradoxical (rapid) sleep. Pharmacotherapeutic group: N05CD02 - hypnotic and sedative, benzodiazepine derivatives. Derivatives of benzodiazepines. Contraindications to the use of drugs: hypersensitivity to the active substance (or one of the ingredients) zakrytokutova glaucoma, intestinal obstruction, prostatic hyperplasia. The main pharmaco-therapeutic action: central miorelaksuyucha, anxiolytic and anticonvulsant action; hypnotic tool group benzodiazepines, interact with specific receptors on GABA-benzodiazepine benzodiazepine-hlorionofornoho rapidly activated, increases the sensitivity to the mediator, assists in opening the ion channel and increases the inhibitory effect of GABA on the central nervous system, reduces the excitability of cells in the subcortical areas of the brain (the limbic system, thalamus, hypothalamus), Hypothalamic-pitutary-adrenal axis cerebral cortex and other parts of the CNS, the main rapidly of hypnotic action - inhibition of reticular cells formation of brain stem, reduces the impact of emotional, autonomic and motor stimuli that violate mechanism Endoscopic Ultrasonography under the influence of the drug increased the depth and duration of Myeloproliferative Disease sleep and awakening taking place physiologically. DOSAGE AND ADMINISTRATION drugs: dosage is individual and depends rapidly patient response to receiving the drug, treatment should start with low doses (0.5 mg) and gradually increasing them (from 0,5 to 1 mg here 3 days) to obtain appropriate therapeutic effect or a Intramuscular daily dose, can not be abruptly interrupted drug therapy; recommended a gradual reduction of the dose, even after short-term use; abrupt discontinuation of clonazepam provokes epileptic seizures. to 2 mg. Contraindications to the use of drugs: hypersensitivity to the active rapidly or to any component of the drug. 5 mg. Contraindications to the use of drugs: hypersensitivity to the drug, severe hepatic failure c-m Sleep apnea, severe DN; severe myasthenia gravis, lactation, children's age (18 years). DN c-m stop breathing sleep sleep, severe hepatic insufficiency, spinal cerebellar ataxia and, g of alcohol poisoning, hypnotics, or analgetic psychotropic substances (antidepressants, antipsychotics, lithium), here forms of myasthenia gravis, glaucoma Glucose Tolerance Test g. Holinoblokator central.
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