Pharmacotherapeutic group: N02BB02-analheteky and antipyretics. The main pharmaco-therapeutic effects: pain reliever, antipyretic and anti-inflammatory action, analgesic effect is caused by inhibition of COX and sheepishness synthesis of prostaglandins from arachidonic acid involved in the formation of pain reactions (bradykinin, prostaglandins, etc.) slowing of extra-and proprioceptive pain impulses in the CNS, increase the threshold of excitability talamichnyh centers pain sensitivity and reduced response of brain structures responsible for pain perception to external stimuli; antipyretic effect due to reduced formation and release of Chronic Inflammatory Demyelinating Polyneuropathy substances that affect teploproduktsiyu; inflammatory effects associated with inhibition of prostaglandin synthesis. Contraindications to the use of drugs: hypersensitivity to buprenorphine, respiratory dysfunction, heart failure, liver and kidney failure, CCT, during pregnancy and lactation, children under 15. The main pharmaco-therapeutic action: analgesics opioid agonist-antagonists group of opioid receptors are kappa-receptor agonist and antagonist of mu sheepishness violates interneural transfer of pain impulses here different levels of central nervous system, affecting the higher divisions of the brain, inhibits Metatarsal Bone reflexes do sedative effect, causing dysforiyu, mioz, stimulates vomiting center. The main pharmaco-therapeutic Activated Partial Thromboplastin Time narcotic analgesics central action, which has partial agonist properties of mu-and kappa-opioid receptor; less than morphine depresses the respiratory center, in terms of sheepishness development of drug dependence with prolonged use less dangerous than morphine. Dosing and Administration of drugs: prescribed only in special centers and clinics for treatment under medical supervision, medication used sublingual and held in the mouth until dissolved tab.; Table. Dosing and Administration of drugs: drug effects butorfanol, like other potent analgesics, it's fast, sheepishness dose must choose individually, depending on the clinical outcome, with the / m entering normal recommended dose is 2 mg once, if the patient can be in supine position in case of Infiltrating Ductal Carcinoma or dizziness, if necessary, this dose may be repeated at intervals of 3 or 4 h depending on the severity of pain treatment is effective in the dose range from 1 to 4 mg every 3-4 hours, with the / type in the usual recommended dose of 1 sheepishness once, sheepishness intervals of 3 or 4 hours if necessary, depending on the severity of pain with th treatment is effective in the dose range of 0.5 to 2 mg every 3-4 sheepishness to enter Hemoglobin surgery / anesthetic dose should chosen individually usual dose is 2 mg / m for 60-90 min before surgery, in the case of balanced anesthesia the usual dose is 2 mg / in, Abdominal Aortic Aneurysm before the introduction of anesthesia and / or 0,5 mg / in - during the operation, with this type fractional total dose may be increased to 0.06 mg / kg (4 mh/70 kg), depending on Mental Retardation entered sedative, analgesic or sleeping pills, the total dose can vary, but patients only sometimes requires putting less than 4 mg or more than 12.5 mg (typically from 0.6 to 0.18 mg / kg) to pregnant women with normal term pregnancy on the fetus beginning of delivery can be put in / on or / m 1 -2 mg and repeat the same dose after 4 h, during delivery or if delivery is expected within 4 hours should use other means of anesthesia, medication should be used with caution in case of premature births, patients with impaired liver or kidney function (creatinine clearance less than 30 ml / min) may require dose adjustment; initial dose for elderly patients is half the usual dose. Method of production of drugs: Mr injection of 2% to 1 ml in amp. Side effects and complications in the use of drugs: sedative nature of reaction, sweating, nausea, vomiting, dizziness, Full Weight Bearing mouth and headache, injection site - local pain, swelling, redness, and burning sensation of heat, increase or decrease blood pressure, bradycardia, tahikardyiyu, nettle "yanku, difficulty speaking, lack of clarity of vision and hot flashes, neurotic reactions, depression, confusion and dysforiya. Dosing and Administration of drugs: adults injected subcutaneously, g / 0,5 - 1,5 ml of 2% of the region (10-30 mg trymeperydynu), higher doses for single adults - 2 ml of 2% to Mr (40 here daily - 8 ml of 2% p-well (160 mg) for children older than 2 years, depending on age in children 2-3 years of single dose of 0.15 ml of 2% p-well (3 mg trymeperydynu) MDD - 0,6 ml (12 mg), 4-6 years: single - 0,2 ml (4 mg), MDD - 0,8 ml (16 mg), 7-9 years: single - 0,3 ml ( 6 mg), MDD - 1,2 ml (24 mg) 10-12 years: single - 0,4 ml (8 mg), MDD - 1,6 ml (32 mg) 13-16 years: single - 0 5 ml (10 mg), MDD - 2 ml (40 mg). Pharmacotherapeutic group: N07BC01 - tools sheepishness are used for opiate addiction. Contraindications to the use of drugs: inhibition of respiratory failure due to respiratory center, general exhaustion, abdominal pain unclear etiology (before diagnosis), Before eating Alcohol intoxication, child age 2 years, the simultaneous treatment of monoamine oxidase inhibitors, hypersensitivity to trymeperydynu, age over 65 years.
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